Osteoporosis – Cannabis Compound Hardens Bone

One more research paper has just been published that shows how plant based substances can help to retain the brittle bone disease, weak bones. Scientists at the Company of Medical Sciences, School of Aberdeen, UK have uncovered how a non-psychoactive compound in cannabis, cannabidiol really helps to maintain bone durability. Wholesale CBD Oil

The endocannabinoid system is a group of cellular receptors that are stimulated by a group of endogenous lipids as well as compounds derived from the cannabis plant. The cannabinoid receptors take part in a variety of physiological processes including cravings control, pain, memory and mood. Recent studies have shown that the endocannabinoid system also has a strong influence on bone metabolism, as the pain are well represented on osteoclasts – cells in whose principal function is to resorb (thin out) bone. 

Bone is the, living tissue that will be continually formed, remodeled and molded in response to both physical and physiological needs of the body. Cuboid matrix consists generally of the macronutrients calcium, magnesium (mg) and phosphate and is the material which enables up both the dense elements of the bone and the bone marrow framework. Various people still assume that if one eats foods abundant with these minerals then they will avoid developing weak bones. Epidemiological and other facts shows that this is not necessarily the circumstance.

In terms of bone health and disease the integrated operations that control the development and resorption bone are just as important as the of calcium, magnesium (mg) and phosphate.

The creation and resorbtion of bone matrix is handled by two main cell types:

1) Osteoblasts are bone cells that are in charge of the formation of bone matrix
2) Osteoclasts are modified white blood cellular material in charge of the resorption of bone tissue.

Both of these cellular types are handled by a complex set of signaling hormones, proteins and cell receptors that reply to the ever-changing requirements on bone tissue and other physiological processes. If perhaps there are very many osteoclasts, or if these cells become overactive, they will resorb more matrix than the osteoblasts will produce. A predominance of osteoclast activity results in the bone becoming less dense – the primary characteristic of the scientific condition known as brittle bones.

The Aberdeen researchers have learned that cannabidiol binds to a specific cannabinoid receptor on the bone-resorbing osteoblast cells. By so doing it inhibits these cells from resorbing the bone matrix – thus helping prevent further decline of the bones.

This kind of is not initially that plant compounds have recently been shown to influence bone metabolism in favour of better bones. In January 2009 researchers at Ok State University in the USA found that, even in the occurrence of oxidative stress and systemic inflammation, polyphenols derived from plums inhibit the action of the bone-softening osteoclasts but enhance the era and process of bone-building osteoblasts.

For those who hope that smoking cooking pot will assist you to strengthen their bones, they certainly so in vain. Even though wild cannabis contains up to 40% cannabidiol, harvested varieties contain very little with this compound. The important point as an end result of this research, in my opinion, is the fact it shows how essential plant compounds are in the prevention of chronic degenerative diseases such as osteoporosis. You will discover limited to be many other phytonutrients in other food plants which may have a positive influence on bone metabolism – they have got not been “discovered” yet.

Although we wait for that research to be taken out, it is important to consume (not smoke) a variety of vegetables, fruit and seasoning to ensure an enough the consumption of a host of beneficial nutrients.